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陈静

发布时间:2022-02-22 发布单位:药学院



陈静,理学博士,副研究员,硕士生导师。2015年毕业于南昌大学食品学院,获得硕士学位。随后于2015年至2020年在韩国中央大学生命学院攻读博士学位,2020年加入暨南大学从事教学科研工作。

近年来主要从事天然化合物药理学研究,聚焦化合物体内外药理学评价及制备运载体系提高化合物体内生物利用度。先后主持并参与2020年、2021年广东省农村科技特派员项目。目前为止共发表SCI论文20余篇,其中以第一作者身份在PhytomedicineFood Funct.J. Agric. Food Chem.J. Funct. Foods等期刊发表论文7篇。

研究方向:

化合物体内外药理活性评价;

制备递送体系提高化合物体内生物利用度研究。

代表性论文:

  1. Qiu S., Zhou Y., Kim J.T., Bao C., Lee H.J., Chen J., Amentoflavone inhibits tumor necrosis factor-α-induced migration and invasion through AKT/mTOR/S6k1/hedgehog signaling in human breast cancer. Food & Function. 2021, 12, 10196-10209.

  2. Chen, J., Qiu, S., Kim, J. T., Cho, J. S., Moon, J. H., Zhou, Y., ... & Lee, H. J., Garcinone C suppresses colon tumorigenesis through the Gli1-dependent hedgehog signaling pathway. Phytomedicine. 2020, 79, 153334.

  3. Chen J., Ko J., Kim J.T., Cho J.S., Qiu S., Kim G.D., Auh J.H, Lee H.J., β-Thujaplicin inhibits basal-like mammary tumor growth by regulating glycogen synthase kinase-3β/β-catenin signaling. Food & Function. 2019, 10, 2691-700.

  4. Chen J., Bao C., Kim J.T., Cho J.S., Qiu S., Lee H.J., Sulforaphene inhibition of adipogenesis via hedgehog signaling in 3T3-L1 adipocytes. Journal of agricultural and food chemistry. 2018, 66, 11926-11934

  5. Chen J., Lee J., Bao C., Kim J.T., Lee H.J., 6, 7, 4′-Trihydroxyisoflavone suppressed the estrogen receptor negative breast cancer growth via regulating glycogen synthase kinase-3β/β-catenin signaling. Journal of Functional Foods. 2018, 48, 498-506.

  6. Chen J., Bao C., Cho S.H., Lee H.J., Green lipped mussel oil complex suppresses lipopolysaccharide stimulated inflammation via regulating nuclear factor-κB and mitogen activated protein kinases signaling in RAW264. 7 murine macrophages. Food science and biotechnology. 2017, 26, 815-22.

  7. Chen, J., He, Q. H., Xu, Y., Fu, J. H., Li, Y. P., Tu, Z., ... & Liu, Y. Y., Nanobody medicated immunoassay for ultrasensitive detection of cancer biomarker alpha-fetoprotein. Talanta. 2016, 147, 523-530.

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联系方式:

Email: chenj@jnu.edu.cn

地址:广东省广州市天河区黄埔大道西610号暨南大学第二理工楼620