主要研究方向:
1. 中药及天然药物抗病毒活性成分研究 2. 抗病毒作用机制研究
近年代表性论文:
1. Guo-Cai Wang, Jia-Gui Li, Guo-Qian Li, Jiao-Jiao Xu, Xia Wu, Wen-Cai Ye*, Yao-Lan Li*. Clerodane diterpenoids from Croton crassifolius. Journal of Natural Products, 2012, 75 (12): 2188-2192.
2. Xia Wu, Lei Wang , Guo-Cai Wang , Hui Wang, Yi Dai, Xin-Xin Yang, Wen-Cai Ye *, Yao-Lan Li*. Triterpenoid saponins from rhizomes of Paris polyphylla var. yunnanensis. Carbohydrate Research, 2013, 368: 1-7.
3. Xia Wu, Lei Wang, Guo-Cai Wang, Hui Wang, Yi Dai, Wen-Cai Ye, and Yao-Lan Li *. New Ste-roidal Saponins and Sterol Glycosides from Paris polyphylla var. yunnanensis. Planta medica, 2012, 78: 1667-1675.
4. Xia Wu, Lei Wang, Hui Wang, Yi Dai, Wen-Cai Ye*, Yao-Lan Li*. Steroidal Saponins from Paris polyphylla var. Yunnanensis. Phytochemistry, 2012, 81: 133-143.
5. Manmei Li, Shuai Wu, Zhong Liu, Wei Zhang, Jing Xu, Ying Wang,Junshan Liu, Dongmei Zhang, Haiyan Tian, Yaolan Li*, Wencai Ye*. Arenobufagin, a bufadienolide compound from toad venom, inhibits VEGFmediated angiogenesis through suppression of VEGFR-2 signaling pathway. Biochem-ical Pharmacology, 2012, 83: 1251-1260.
6. Peng Wu, Miao-Xian Su, Ying Wang, Guo-Cai Wang, Wen-Cai Ye, Hau-Yin Chung, Juan Li, Ren-Wang Jiang*, and Yao-Lan Li*. Supercritical fluid extraction assisted isolation of new ses-quiterpene lactones with antiproliferative effect from Centipeda minima. Phytochemistry, 2012, 76: 133-140.
7. Ying Wang, Mei Chen, Jing Zhang, Xiao-Li Zhang, Xiao-Jun Huang, Xin Wu, Qing-Wen Zhang, Yao-Lan Li*, Wen-Cai Ye*. Flavone C-glycosides from the leaves of Lophatherum gracile and their in vitro antiviral activity. Planta medica, 2012, 78: 46-51.
8. Wing-Shan Ho, Junyi Xue, Samuel S.M. Sun, Vincent E.C. Ooi and Yaolan Li*. Antiviral activ-ity of daphnoretin isolated from Wikstroemia indica, Phytotherapy Research, 2010, 24: 657-661.
9. Weihuan Huang, Xiaoli Zhang, Yifei Wang, Wencai Ye, Vincent E C Ooi, Hau Yin Chung and Yao lan Li*. Antiviral biflavonoids from Radix Wikstroemiae (Liaogewanggen), CHENISES MEDICINE, 2010, 5:23.
10. Guocai Wang, Ying Wang, Xiaoqi Zhang, Yaolan Li, Xinsheng Yao, Wencai Ye. Securinega alkaloids from Flueggea leucopyra. Chemical & pharmaceutical bulletin, 2010, 58(3): 390-393.
11. Weihuan Huang, Yaolan Li*, Hui Wang, Miaoxian Su, Zhenyou Jiang, Vincent E. C. Ooi and Hau Yin Chung. Toxicological Study of a Chinese Herbal Medicine, Wikstroemia indica. Natural Product Communications, 2009, 4 (9): 1227-1230.
12. Yaolan Li, Chung-Man Yeung, Lawrence C. M. Chui, Ying-Zhou Cen and Vincent E. C. Ooi. Chemical composition and antiproliferative Activity of essential oil from the leaves of a medicinal herb, Schefflera heptaphylla, Phytotherapy Research, 2009, 23: 140-142.
发明专利:
1.李药兰,岑颖洲,许少玉,伍秋明,苏妙贤,具抗病毒作用的小紫金牛提取物及其提取方法和用途,公开发明专利,申请号:200510101981.X,公开号:CN1872101,授权:2010年1月27日。
2.药凤荷,;李药兰,黄荣春,黄詹秀美,新的黄烷衍生物及其制备方法和用途.申请号:200410051988.0。公开号:CN1305870,授权:2007年3月21日。
3.李药兰,岑颖洲,许少玉,黄伟欢,了哥王提取物及其制备方法和用途,申请号:200910040995.3。公开号:CN101601666,授权:2011年5月25日。
4.李药兰吴鹏,叶文才,张晓琦,王英.一种鹅不食草总倍半萜内酯提取物及其制备和应用.申请号:200910213741.7.公开号:CN101732383 B,授权:2012年1月11日。
5.李药兰,叶文才,张晓琦,王英,范春林。异荭草苷作为制备抗呼吸道合胞病毒的药物的用途.申请号:201010178799.5. 公开号:CN101843612 B,授权:2011年1月11日。
6.李药兰,叶文才,王英,王国才,张晓琦,范春林.淡竹叶提取物及其制备方法和用途.申请号:201110124349.2。
7.李药兰,叶文才,王国才,王英,张晓琦,张冬梅.咖啡酰衍生物及其在制备抗呼吸道合胞病毒药物中的用途.申请号:201110101619.8。
8.李药兰,叶文才,吴霞,王国才,王英,张晓琦,张冬梅.地胆草提取物及其制备方法和在制备抗病毒药物中的用途.申请号:201110101650.1。