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申丽
发布时间:2014-07-18
申丽,女,1982年5月生,博士,副教授。2010年3月于华东理工大学应用化学专业获得博士学位。博士期间研究方向为绿色化学及氟化学,先后参与了绿色农药创制及无溶剂条件下的新型多组分反应合成氮杂环及其含氟衍生物的研究工作;2010年5月-2012年4月赴美国夏威夷大学希洛分校药学院进行博士后研究工作,从事具有抗感染及抗癌活性的天然产物小分子的结构修饰,设计及合成等方面研究工作;2013年1月加入暨南大学药学院。至今已发表SCI论文16篇,其中第一作者8篇。
 
主要研究方向:
1.活性天然产物分子的合成与结构修饰
2.海洋药物的设计、合成及构效关系研究
 
代表性论文:
1.   Li Shen, Song Cao*, Jingjing Wu, Jian Zhang, Hui Li, Nianjin Liu, Xuhong Qian*. A Revisit to Hantzsch Reaction: Unexpected products beyond 1,4-dihydropyridines. Green Chem., (11): 1414-1420, 2009.
2.  Li Shen, Eun-Jung Park, Tamara P. Kondratyuk, Daniela Guendisch, Laura Marler, John M. Pezzuto, Anthony D. Wright, Dianqing Sun*. Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents. Bioorg. Med. Chem., 19(21), 6182-6195, 2011.
3.  Li Shen, Charles J. Simmons, Dianqing Sun*. Microwave-assisted synthesis of macrocycles via intramolecular and/or bimolecular Ullmann coupling. Tetrahedron Lett., 53(32), 4173-4178, 2012.
4.  Li Shen, Dianqing Sun*. Total synthesis and structural revision of engelhardione. Tetrahedron Lett., 52(35), 4570-4574, 2011.
5.  Li Shen, Song Cao*, Jingjing Wu, Hui Li, Jian Zhang, Mingxi Wu, Xuhong Qian*. K2CO3-assisted one-pot sequential synthesis of 2-trifluoromethyl-6-difluoromethylpyridine-3,5-dicarboxylates under solvent-free conditions. Tetrahedron Lett., 51 (37), 4866-4869, 2010.
6.  Li Shen, Song Cao*, Nianjin Liu, Jingjing Wu, Longjie Zhu, Xuhong Qian*. Ytterbium(III) perfluorooctanoate-catalyzed one-pot three-component synthesis of fully substituted pyrazoles under solvent-free conditions. Synlett, (9): 1341-1344, 2008.
7.  Li Shen, Jian Zhang, Song Cao*, Jinlong Yu, Nianjin Liu, Jingjing Wu, Xuhong Qian*. One-pot synthesis of trifluoromethyl-containing pyrazoles via sequential Yb(PFO)3-catalyzed three-component reaction and IBX-mediated oxidation. Synlett, (19), 3058-3062, 2008.
8.  Li Shen, Marcus M Maddox, Sudip Adhikari, David F Bruhn, Manish Kumar, Robin E Lee, Julian G Hurdle, Richard E Lee, Dianqing Sun*. Syntheses and evaluation of macrocyclic engelhardione analogs as antitubercular and antibacterial agents. J. Antibiot., 2013, online, Doi:10.1038/ja.2013.21.
 
主要社会兼职:
美国化学会会员
北美植物化学会会员
 
联系方式:
E-mail:Shenli6052@sina.com