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徐东升

发布时间:2022-09-30 发布单位:药学院


1、个人简介

徐东升,男,博士,副教授,广东省药学会生物医药分析专业委员会委员,主要从事药物分析新方法及分离科学理论的研究。20202月毕业于西班牙阿尔卡拉大学分析化学专业,获博士学位。2020年于暨南大学药学院中药学博士后流动站从事博士后研究。2022年进入暨南大学药学院药物分析研究中心工作。已在TrAC Trends in Analytical Chemistry, Chemical Engineering Journal, Journal of Chromatography A, Journal of Pharmaceutical Analysis, Journal of Chromatography Open, Journal of Pharmaceutical and Biomedical Analysis等国际权威SCI期刊上发表论文10余篇,已主持国家自然科学基金青年项目,中国博士后基金面上项目,广东省基础与应用基础研究区域联合基金项目。

2、讲授课程

《中药分析学》

3、研究方向

1. 手性药物分离

2. 疾病标志物分子诊断

3. 微纳流分离分析新方法

4、学术兼职

广东省药学会生物医药分析专业委员会委员

5、主持科研项目

1. 国家自然科学基金,青年基金(82104115),基于新型polyHIPE材料的类风湿性关节炎早期诊断标志物的富集方法研究,2022-2024,主持

2. 中国博士后科学基金,面上项目(2021M691252),基于新型 Pickering-高内相比聚合材料免抗富集技术的单抗药精准定量分析研究,2021-2022,主持

3.广东省基础与应用基础研究基金区域联合基金,青年基金(2020A1515110867),基于配体垂钓-活性测试一体化的中药复方抗流感病毒PAN抑制剂的筛选研究,2020-2023,主持

6、代表性论文

1. Lingjue Sun#, Dongsheng Xu#, Yuan Shen#, J. Crommen, Qiqin Wang, Zhengjin Jiang; Photo-assisted generation of versatile zwitterionic carboxybetaine-based hypercrosslinked polymers for separation science, Chemical Engineering Journal, 2021, 5, 133374.

2. Dongsheng Xu#, E. Sanchez-Lopez, Qiqin Wang, Zhengjin Jiang, M. L. Marina. Determination of L-norvaline and L-tryptophan in dietary supplements by nano-LC using an O-[2-(methacryloyloxy)-ethylcarbamoyl]-10,11-dihydroquinidine-silica hybrid monolithic column,Journal of Pharmaceutical Analysis, 2020, 10: 70-77.

3. Dongsheng Xu#, Qiqin Wang, E. Sanchez-Lopez, Zhengjin Jiang, M. L. Marina. Preparation of an O-[2-(methacryloyloxy)-ethylcarbamoyl]-10,11-dihydroquinidine-silica hybrid monolithic column for the enantioseparation of amino acids by nano-liquid chromatography,Journal of Chromatography A, 2019, 1593: 63-72.

4. Dongsheng Xu#, Huikai Shao, Rongying Luo, Qiqin Wang, E. Sanchez-Lopez, S. Fanali, M. L. Marina, Zhengjin Jiang. A facile and efficient single-step approach for the fabrication of vancomycin functionalized polymer-based monolith as chiral stationary phase for nano-liquid chromatography, Journal of Chromatography A, 2018, 1557: 43-50.

5. Jincai Wang#, Xianglong Zhao#, Dongsheng Xu#, Liang Lai, J. Crommen, Jialiang Guo, Zhengjin Jiang. Development of acidic phospholipid containing immobilized artificial membrane column to predict drug-induced phospholipidosis potency, Journal of Chromatography A, 2021, 1647: 462147.

6. Dongsheng Xu#, Huikai Shao, Liang Lai, E. Sanchez-Lopez, M. L. Marina, Zhengjin Jiang. Single-step fabrication of a teicoplanin functionalized organic-silica hybrid monolith for enantioseparation by nano-liquid chromatography, Journal of Chromatography Open, 2021, 1: 100008.

7. Jialiang Guo#, Qiqin Wang#, Dongsheng Xu, J. Crommen, Zhengjin Jiang. Recent advances in preparation and applications of monolithic chiral stationary phases, TrAC Trends in Analytical Chemistry, 2020, 123:115774.

8. Huikai Shao#, Liang Lai#, Dongsheng Xu, J. Crommen, Qiqin Wang, Zhengjin Jiang. Development of zirconium modified adenosine triphosphate functionalized monolith for specific enrichment of N-glycans, Journal of Chromatography A, 2021, 1644: 462090.

9. Haibin Li#, Chusheng Liu, Li Zhao, Dongsheng Xu, Tingting Zhang, Qiqin Wang, Deirdre Cabooter, Zhengjin Jiang. A systematic investigation of the effect of sample solvent on peak shape in nano- and microflow hydrophilic interaction liquid chromatography columns, Journal of Chromatography A, 2021, 1655: 462498.

10. Rongying Luo#, Hai Han#, Jia Liu, Dongsheng Xu, Qiqin Wang, S. Fanali, Zhengjin Jiang. Preparation and application of teicoplanin functionalized polymeric monolith for enantioseparation of chiral drugs, Journal of Pharmaceutical and Biomedical Analysis, 2020, 182: 113129.

7、联系方式

地址:广东省广州市番禺区兴业大道东855号暨南大学药学院

邮箱:dongshengxu@jnu.edu.cn