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谭毅

发布时间:2022-05-08 发布单位:药学院

1、个人简介:

谭毅,理学博士,副研究员,硕士生导师。20056月毕业于衡阳师范学院化学专业,获学士学位;20126月,获华南理工大学无机化学专业硕士学位;20182月获香港城市大学化学生物学专业博士学位;20185月至20213月在香港大学化学系李学臣教授课题组从事博士后研究工作;20214月入职暨南大学药学院从事教学科研工作。以第一作者在J. Am. Chem. Soc., Angew. Chem. Int. Ed., ACS Appl. Mater. Interfaces等国际著名期刊发表SCI论文7篇。

2、讲授课程:

1)《有机化学》

2)《有机化学II

3、研究方向:

1)小分子共价抑制剂的开发与研究

2)天然产物靶标发现与确证

3)肽类/拟肽类药物的设计与合成

4、代表性论文和专著:

[1] Y. Tan, H. Wu, T. Wei, and X. Li*, Chemical Protein Synthesis: Advances, Challenges and Outlooks. J. Am. Chem. Soc. 2020, 142, 20288-20298. (IF: 15.4)

[2] Y. Tan, J. Li, K. Jin, J. Liu, Z. Chen, J. Yang, and X. Li*, Cysteine/Penicillamine Ligation Independent of Terminal Steric Demands for Chemical Protein Synthesis. Angew. Chem. Int. Ed. 2020, 59, 12741-12745. (IF: 15.3)

[3] Y. Tan, L. Zhang, K. H. Man, R. Peltier, G. Chen, H. Zhang, L. Zhou, F. Wang, D. Ho, S. Q. Yao, Y. Hu*, and H. Sun*, Reaction-Based OFF-ON Near-infrared Fluorescent Probe for Imaging Alkaline Phosphatase Activity in Living Cells and Mice. ACS Appl. Mater. Interfaces. 2017, 9, 6796-6803. (IF: 9.2)

[4] Y. Tan, R. Liu, H. Zhang, R. Peltier, Y. Lam, Q. Zhu, Y. Hu, and H. Sun*, Design and Synthesis of Near-infrared Fluorescent Probes for Imaging of Biological Nitroxyl. Scientific Reports 5, 2015, 16979. (IF: 4.3)

[5] Y. Tan, Z. Fu* Y. Zeng, H. Chen, S. Liao, J. Zhang, and J. Dai, Highly Stable Photochromic Crystalline Material Based on a Close-Packed Layered Metal-Viologen Coordination Polymer. J. Mater. Chem., 2012, 22, 17452-17455. (IF: 6.6)

[6] Y. Tan, H. Chen, J. Zhang, S. Liao, J. Dai, and Z. Fu*, Synthesis of a 3D Photochromic Coordination Polymer with an Interpenetrating Arrangement: Crystal Engineering for Electron Transfer Between Donor and Acceptor Units. CrystEngComm, 2012, 14, 5137-5139. (IF: 3.5)

[7] Y. Tan, Z. Fu*, and J. Zhang, A Layered Amino-Functionalied Zinc-Terephthlate Metal Organic Framework: Structure, Characterization and Catalytic Performation for Knoevenagel Condensation. Inorg. Chem. Commun., 2011, 14, 1966-1970. (IF: 2.5)

[8] Z. Fu*, Yi Tan, J. Zhang, S. Liao, D. Su, H. Chen, Y. Yu, and J. Peng, An Efcient Basic Catalyst Based on a New Germanium Coordination Complex. Inorg. Chem. Commun., 2012, 15, 221-224. (IF: 2.5)

[9] J. Liu, T. Wei, Y. Tan, H. Liu and X. Li*, Enabling Chemical Protein (Semi)synthesis via Reducible Solubilizing Tags (RSTs), Chem. Sci., 2022, 13, 1367-1374. (IF: 9.8)

[10] L. Zhou, Q. Wang, Y. Tan, Matthew J. Lang, H. Sun* and X. Liu*. Rational Development of Near-Infrared Fluorophores with Large Stokes Shifts, Bright One-Photon, and Two-Photon Emissions for Bioimaging and Biosensing Applications. Chem. Eur. J. 2017, 23, 8736-8740. (IF: 5.2)

5、联系方式:

联系邮箱:tanyi@jnu.edu.cn