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黄郑炜

发布时间:2022-07-11 发布单位:药学院



        黄郑炜,男,博士,副教授,硕士生导师,暨南大学“青蓝学者”。博士后合作导师为国家级人才称号获得者丁克教授。2020年毕业于中山大学药学院药剂学专业,获理学博士学位,导师为国家特聘专家吴传斌教授。2015年获中山大学理学学士学位及优秀毕业生称号。本人专业方向为药剂学,主要从事药物制剂的基础和应用研究。近年来参与各级科研项目4项,其中国家自然科学基金项目1项。相关研究成果已发表多篇国际专业期刊论文,其中以本人为(共同)第一作者或(共同)通讯作者身份的研究论文共29篇,公开申请专利3件。此外,担任多个学术期刊编委和学术团体会员。


研究方向:

    铁死亡纳米制剂

    肺部吸入纳米制剂

    纳米制剂的体内命运

    纳米制剂-生物分子相互作用


代表性科研项目:

    1.国家自然科学基金青年科学基金项目(82104070),基于“限域-分凝”策略的多肽药物吸入气雾剂的构建及其稳定性调控机制探究(202201-202412月,30万元)

    2.暨南大学中央高校基本科研业务费项目(21621012),兼得“鱼”与“熊掌”:高稳定性、高载药量多肽药物吸入气雾剂的构建及其稳定性调控原理研究(202101-202212月,9万元)

    3.广州市基础研究计划基础与应用基础研究项目(202201010589),水分子冷冻结晶速率对用于多肽药物吸入气雾剂的“限域-分凝”系统负载能力的调控机理探究(202204-202403月,5万元)

    4.广东省级药学实验教学示范中心建设项目(N.A.),基于微热量热法的药物与载体间相互作用研究(201307-201407月,0.25万元)


代表性论文:

    1.W. Wang†, Z. Huang†, Y. Huang†, X. Zhang, J. Huang, Y. Cui, X. Yue, C. Ma, F. Fu, W. Wang, C. Wu, X. Pan*. Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches. Adv Drug Deliver Rev. 2022; 185: 114309. (IF = 17.873)

    2.W. Wang†, Z. Huang†, Y. Li, W. Wang, J. Shi, F. Fu, Y. Huang*, X. Pan, C. Wu**. Impact of particle size and pH on protein corona formation of solid lipid nanoparticles: A proof-of-concept study. Acta Pharm Sin B. 2021; 11(4): 1030-1046. (IF = 14.911)

   3.Z. Huang, Y. Huang, W. Wang, F. Fu, W. Wang, S. Dang, C. Li, C. Ma, X. Zhang, Z. Zhao, X, Pan*, C. Wu. Relationship between particle size and lung retention time of intact solid lipid nanoparticle suspensions after pulmonary delivery. J Control Release. 2020; 325: 206-222. (IF = 11.467)

    4.W. Wang†, H. Liu†, Z. Huang*, F. Fu, W. Wang, L. Wu, Y. Huang**, C. Wu, X. Pan***. The effect of organic ligand modification on protein corona formation of nanoscale metal organic frameworks. Chinese Chem Lett. 2022; 33: 4185-4190. (IF = 8.455)

    5.Z. Zhao†, Z. Huang†, X. Zhang, Y. Huang*, Y. Cui, C. Ma, G. Wang, T. Freeman, X. Lu, X. Pan, C. Wu**. Low density, good flowability cyclodextrin-raffinose binary carrier for dry powder inhaler: Anti-hygroscopicity and aerosolization performance enhancement. Expert Opin Drug Del. 2018; 15(5): 443-457. (IF = 8.129)

    6.C. Zhou†, Z. Huang†, Y. Huang†, B. Wang, P. Yang, Y. Fan, A. Hou, B. Yang, Z. Zhao, G. Quan, X. Pan*, C. Wu. In-situ gelation of rhEGF-containing liquid crystalline precursor with good cargo stability and system mechanical properties: A novel delivery system for chronic wounds treatment. Biomater Sci. 2019; 7: 995-1010. (IF = 7.590)

    7.Z. Huang†, H. Wu†, B. Yang, L. Chen, Y. Huang, G. Quan, C. Zhu, X. Li, X. Pan*, C. Wu. Anhydrous reverse micelle nanoparticles: New strategy to overcome sedimentation instability of peptide-containing pressurized metered-dose inhalers. Drug Deliv. 2017; 24(1): 527-538. (IF = 6.819)

    8.Y. Yang†, Z. Huang†, X. Zhang, J. Li, Y. Huang*, W. Chen, X. Pan**, C. Wu. Development of paroxetine hydrochloride single layer controlled-release tablets based on 32 factorial design. Pharmaceutics. 2018; 10(243): 1-19. (IF = 6.525)

    9.Z. Huang, L. Lin, C. Goverin, H. Liu, L. Wang, Q. Zhou, M. Lu*, C. Wu. Dry powder inhaler formulations of poorly water-soluble itraconazole: A balance between in-vitro dissolution and in-vivo distribution is necessary. Int J Pharm. 2018; 551: 103-110. (IF = 6.510)

    10.Z. Huang†, L. Shu†, Y. Huang*, C. Wu, X. Pan**. Low drug loading hampers the clinical translation of peptide drugs-containing metered-dose inhalers. Pharmaceuticals. 2022; 15(4): 389. (IF = 5.215)


主要学术任职:

1.SCI期刊Journal of Tropical Medicine编委

2.英文期刊Acupuncture and Herbal MedicineHealth Care ScienceInfectious Medicine青年编委SCI期刊Expert Opin Drug DelMat Sci Eng C-MaterInt J PharmJ Drug Deliv Sci TechDrug Dev Ind Pharm审稿人

3.2019.10-至今:中国药学会(CPA中国微米纳米技术协会(CSMNT)会员


主要专利情况:

1.黄郑炜,张雪娟,吴传斌,潘昕,黄莹,付芳琴,白雪群,王文浩.用于吸入气雾剂的低制冷效应复合抛射剂及其制备方法和应用.申请号: CN2022101631104.公告公开日: 2022-05-24.

2.张雪娟,黄郑炜,黄莹,吴传斌,周钥,王冠林,翟紫照.硫酸多黏菌素B/棉子糖干粉及其吸入粉雾剂和制备方法.申请号: CN202210061115.6.公告公开日: 2022-06-14.

3.吴传斌,张雪娟,崔影彤,周钥,王冠林,潘昕,黄莹,黄郑炜,李峰,陈航平,冯地桑,许日龙. ε-聚赖氨酸干粉、ε-聚赖氨酸吸入粉雾剂及其制备方法.申请号: CN202111137953.9.公告公开日: 2021-12-10.


主要获奖情况:

1. 2020美国药学科学家协会年会(2020 AAPS Pharmsci 360)最佳摘要奖(2020年)

2.《今日药学》杂志2017年度优秀论文三等奖(2017年)


办公地点:暨南大学番禺校区药学院大楼

邮箱:huangzhengw@jnu.edu.cn