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姚志红

发布时间:2019-11-19 发布单位:药学院

姚志红


个人简介:

姚志红,女,博士,教授、硕士生/博士生导师。十八年来活跃在暨南大学药学院教学科研第一线。先后承担6本科生中文/全英文课程和2硕士生课程负责或主讲)近4000学时;已培养硕士生18名、协助培养博士生7名及硕士生171名入选博士优秀毕业生、3名获国家奖学金、2名获校学术创新成果奖、1名获广东省药学优秀研究生学术论文二等奖)并完成2名博士后的合作指导。近年研究兴趣围绕中药及复方药效物质的揭示,针对中药复方制剂仙灵骨葆胶囊、芪苈强心胶囊、丹蒌片和中药经典方栝楼薤白半夏汤、补中益气汤、温胆汤及药食同源中药薤白、枳实、姜等开展中药药代动力学及质量控制方法研究。主持承担了国家自然科学基金面上项目3项、广东省自然科学基金面上项目等省部级课题5项及厅局级项目2项;作为合作方负责人承担了国家重点研发计划子课题1项、作为主要成员完成国家自然科学基金重大国际合作项目和中港合作项目各1项、科技部十二五重大新药创制专项2项;主持企业课题3项;牵头获纵向/横向科研经费700万元。近五年作为第一作者或者通讯作者在Phytomedicine, J. Ethnopharmacol., J. Agric. Food. Chem., J. Pharm. Biomed. Anal., Food Chem., Food & Funct. 等国际知名学术期刊发表SCI收录的研究论文30余篇并在中文核心期刊发表研究论文8篇;作为第一完成人申请获中国发明专利授权1项;获广州市科技进步三等奖1项。

 

目前负责/主讲课程: 

研究生课程:中药质量控制方法与技术 

本科生课程: 药物分析; 药物分析实验; 现代分析技术; 现代分析技术(全英文)

        

研究生招生方向:

中药药代及复杂生物样品分析技术(博士生招生)

色谱联用技术在药物分析中的应用(硕士生招生)

 

近五年代表性研究论文(通讯作者, 选填10篇):

[1] The discovery of Q-markers of Qiliqiangxin Capsule, a traditional Chinese medicine prescription in the treatment of chronic heart failure, based on a novel strategy of multi-dimensional radar chartmode evaluation. Phytomedicine, 2021, 82: 153443.  (Impact factor: 4.268; A1-; Corresponding author)

[2] Chemical profile of Cimicifuga heracleifolia Kom. And immunomodulatory effect of its representative bioavailable component, cimigenoside on Poly (I: C)-induced airway inflammation. Journal of Ethnopharmacology, 2021, 267: 113615. (Impact factor: 3.690; A2-; Corresponding author)

[3] Qualitative and quantitative analysis of the chemical profile for Gualou-Xiebai-Banxia decoction, a classical traditional Chinese medicine formula for the treatment of coronary heart disease, by UPLC-Q/TOF-MS combined with chemometric analysis. Journal of Pharmaceutical and Biomedical Analysis, 2021, 197: 113950. (Impact factor: 3.209; A2-; Corresponding author)

[4] Characterization of chemical profile and quantification of representative components of DanLou tablet, a traditional Chinese medicine prescription, by UHPLC-Q/TOF-MS combined with UHPLC-TQ-MS. Journal of Pharmaceutical and Biomedical Analysis, 2020, 180, 113070. (Impact factor: 3.209; A2-; Corresponding author)

[5] In vivo metabolic profiles of Bu-Zhong-Yi-Qi-Tang, a famous traditional Chinese medicine prescription, in rats by ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2019, 171: 81-98. (Impact factor: 2.983; A2-; Corresponding author)

[6] Mucosal immunomodulatory evaluation and chemical profile elucidation of a classical traditional Chinese formula, Bu-Zhong-Yi-Qi-Tang.  Journal of Ethnopharmacology, 2019, 228: 188-199. (Impact factor: 3.115; A2-; Corresponding author)

[7] Chemical inhibition and stable knock-down of efflux transport leads to reduced glucuronidation of wushanicaritin in UGT1A1-overexpressing HeLa cells: The role of breast cancer resistance protein (BCRP) and multidrug resistance-associated proteins (MRPs) in the excretion of glucuronides. Food & Function, 2018, 9(3): 1410-1423. (Impact factor: 3.289; A1- I; Corresponding author) 

[8] Metabolic profiles of ginger, a functional food, and its representative pungent compounds in rats by ultraperformance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry. Journal of Agricultural and Food Chemistry, 2018, 66(34): 9010-9033. (Impact factor: 3.412; A1-I; Corresponding author)

[9] In vitro glucuronidation of wushanicaritin by liver microsomes, intestine microsomes and expressed human UDP-Glucuronosyltransferase enzymes. International Journal of Molecular Science, 2017, 18(9): 1-17. (Impactor factor: 3.687; A2-; Corresponding author)

[10] Study on chemical profiles and metabolites of Allii Macrostemonis Bulbus as well as its representative steroidal saponins in rats by ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry. Food Chemistry, 2016, 192: 499-515.(Impactor factor: 4.946; A1-; Corresponding author)